Antimicrobial Resistance Profile in ICU Patients Across India: A Multicenter, Retrospective, Observational Study

A study evaluating antimicrobial resistance (AMR) profiles in ICU patients across India found that gram-negative bacteria were more common than gram-positive bacteria in causing antibiotic-resistant infections. The majority of patients were males and adults, with the median age being 58 years. The commonest gram-positive bacteria were S. aureus, Coagulase-negative Staphylococci, and Enterococcus spp. The most common gram-negative bacteria were Klebsiella pneumoniae, Escherichia coli, and Acinetobacter spp. The study concluded that evaluation based on MDR and antibiotic consumption patterns is imperative for physicians to decide on the best empirical treatment for nosocomial infections caused by multidrug-resistant (MDR) strains, such as methicillin-resistant Staphylococcus aureus (MRSA).